As stated above, Parkinson's is caused by the lack of dopamine production by neurons in the brain that act on a specific area in the brain called the substantia nigra. Dopamine is a chemical messenger that is responsible for relaying signals from the substantia nigra to other parts of the brain to initiate movements of the body. Symptoms of Parkinson's disease appear when there is damage to about 60-80 percent of the dopamine-producing cells in the brain. When the brain cells become impaired it is called Neurodegeneration.
Parkinson's Disease is a motor system disorder that is a slow progressing disease in most people. The disease is the result of a loss of brain cells that produce dopamine. The brain slowly stops producing dopamine which can take years to develop and people can live for many years with the disease. Dopamine is a neurotransmitter that is responsible for the regulation of body movements and emotions. Currently, Parkinson's is incurable but is not a fatal disease on it's own.
Some of the symptoms of Parkinson's disease are tremors of the body including the limbs, face, and stiffness in the body. In addition, slower movements and lack of coordination are also symptoms of Parkinson's Disease. As the disease progresses over time, the patient will have more difficultly completing everyday tasks including walking, chewing, talking, and sleeping. In some cases, the disease will progress quicker than others. The disease also effects emotional stability in the patient and could cause emotional changes as well.
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This image depicts the location in the brain where the Substantia
nigra cells are located (Disease Pictures).
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Even though Parkinson's disease is not fatal, it is rated one of the top causes of death in the United States due to the complications that go along with this condition. When you go in to see a doctor with these symptoms, your doctor may order brain scans or blood work as well as other tests to rule out the possibilities of other possible conditions. Once you are diagnosed with Parkinson's Disease, the goal of your health care providers is to make you life as comfortable as possible.
References
Disease Pictures (n.d.). Retrieved November 23, 2016, from http://diseasespictures.com/wp-content/uploads/2012/11/Parkinsons-Disease-5.jpg
NINDS | Parkinson's Disease Information Page. (n.d.). Retrieved November 20, 2016, from http://www.ninds.nih.gov/
National Parkinson Foundation: Believe in Better. Retrieved November 19, 2016, from http://www.parkinson.org/
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